Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM27073'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM27073 ((1R,5S)-3-[(2S)-2-[(tert-butylcarbamoyl)amino]-3,3...) Show SMILES CC[C@H](NC(=O)C1[C@@H]2[C@H](CN1C(=O)[C@@H](NC(=O)NC(C)(C)C)C(C)(C)C)C2(C)C)B1O[C@@H]2CC3CC(C3(C)C)[C@]2(C)O1 |r| Show InChI InChI=1S/C32H55BN4O5/c1-13-21(33-41-20-15-17-14-19(30(17,8)9)32(20,12)42-33)34-25(38)23-22-18(31(22,10)11)16-37(23)26(39)24(28(2,3)4)35-27(40)36-29(5,6)7/h17-24H,13-16H2,1-12H3,(H,34,38)(H2,35,36,40)/t17?,18-,19?,20+,21-,22-,23?,24+,32-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	380	-37.3	n/a	n/a	n/a	n/a	n/a	6.5	30
Schering-Plough Research Institute					Assay Description Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...				Bioorg Med Chem Lett 19: 180-3 (2009) Article DOI: 10.1016/j.bmcl.2008.10.124 BindingDB Entry DOI: 10.7270/Q2SX6BH6
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