Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM288011'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepatitis C virus (HCV))	BDBM288011 (US10087167, Compound 4020) Show SMILES CNC(=O)c1c(oc2cc(N(CCF)S(C)(=O)=O)c(cc12)-c1cccc(c1)C(=O)N1CC[C@H](F)C1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C30H28F3N3O5S/c1-34-29(37)27-24-15-23(19-4-3-5-20(14-19)30(38)35-12-10-22(33)17-35)25(36(13-11-31)42(2,39)40)16-26(24)41-28(27)18-6-8-21(32)9-7-18/h3-9,14-16,22H,10-13,17H2,1-2H3,(H,34,37)/t22-/m0/s1	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...				US Patent US10087167 (2018) BindingDB Entry DOI: 10.7270/Q2445PGP
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