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Found 1 hit Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM29337'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Genome polyprotein


(Hepatitis C virus genotype 1b (isolate Taiwan))		BDBM29337
PNG
(US9688816, D | triphenylmethane derivative, 9)
Show SMILES CC(c1ccccc1)(c1ccc(O)cc1)c1ccc(O)cc1
Show InChI InChI=1S/C20H18O2/c1-20(15-5-3-2-4-6-15,16-7-11-18(21)12-8-16)17-9-13-19(22)14-10-17/h2-14,21-22H,1H3
PDB
MMDB

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MCE
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PC sid
UniChem

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Article
PubMed
n/an/an/an/an/an/an/a7.022



National Taiwan University



Assay Description
The enzyme was assayed the DNA helicase activity by using DNA substrate (annealed BHQ1-labeled release strand and FITC-labeled template strand) in th...

J Med Chem 52: 2716-23 (2009)


Article DOI: 10.1021/jm8011905
BindingDB Entry DOI: 10.7270/Q2RF5SBT
More data for this
Ligand-Target Pair