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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM486277'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Genome polyprotein


(Hepatitis C virus genotype 3a (isolate k3a) (HCV))		BDBM486277
PNG
(US10947210, Compound 14-7A)
Show SMILES CNC(=O)c1c(oc2cc(N(CCOCCOCCOc3ccccc3C(O)=O)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(F)cc1
Show InChI InChI=1S/C33H35FN2O9S/c1-35-32(37)30-26-19-25(21-7-8-21)27(20-29(26)45-31(30)22-9-11-23(34)12-10-22)36(46(2,40)41)13-14-42-15-16-43-17-18-44-28-6-4-3-5-24(28)33(38)39/h3-6,9-12,19-21H,7-8,13-18H2,1-2H3,(H,35,37)(H,38,39)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



COCRYSTAL PHARMA, INC.

US Patent


Assay Description
The reaction mixtures consisted of 50 mM Hepes-KOH, pH 7.5, 5 mM MgCl2, 5 mM DTT, 2% glycerol, 0.01% Triton® X-100, 0.5 uM polyA:U16 substrate, purif...

US Patent US10947210 (2021)


BindingDB Entry DOI: 10.7270/Q2CZ3B8J
More data for this
Ligand-Target Pair