Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM50486105'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepacivirus C)	BDBM50486105 (CHEMBL2203886) Show SMILES [H][C@@]12C[C@H](N(C1)C(=O)[C@@H](NC(=O)N1CCC[C@@]([H])(C1)OCCCc1cc3c(O2)cc(OCC)nc3cc1OC)C1CCCCC1)C(=O)N[C@@]1(C[C@H]1C=C)C(=O)NS(=O)(=O)C1CC1 |r| Show InChI InChI=1S/C43H58N6O10S/c1-4-28-23-43(28,41(52)47-60(54,55)31-15-16-31)46-39(50)34-20-30-25-49(34)40(51)38(26-11-7-6-8-12-26)45-42(53)48-17-9-14-29(24-48)58-18-10-13-27-19-32-33(21-35(27)56-3)44-37(57-5-2)22-36(32)59-30/h4,19,21-22,26,28-31,34,38H,1,5-18,20,23-25H2,2-3H3,(H,45,53)(H,46,50)(H,47,52)/t28-,29+,30-,34+,38+,43-/m1/s1	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of HCV genotype 1b BK NS3/4A protease A156T mutant expressed in Escherichia coli incubated for 30 mins by time-resolved fluorescence assay				Bioorg Med Chem Lett 22: 7207-13 (2012) Article DOI: 10.1016/j.bmcl.2012.09.061 BindingDB Entry DOI: 10.7270/Q28D0041
					More data for this Ligand-Target Pair
Genome polyprotein (Hepacivirus C)	BDBM50486105 (CHEMBL2203886) Show SMILES [H][C@@]12C[C@H](N(C1)C(=O)[C@@H](NC(=O)N1CCC[C@@]([H])(C1)OCCCc1cc3c(O2)cc(OCC)nc3cc1OC)C1CCCCC1)C(=O)N[C@@]1(C[C@H]1C=C)C(=O)NS(=O)(=O)C1CC1 |r| Show InChI InChI=1S/C43H58N6O10S/c1-4-28-23-43(28,41(52)47-60(54,55)31-15-16-31)46-39(50)34-20-30-25-49(34)40(51)38(26-11-7-6-8-12-26)45-42(53)48-17-9-14-29(24-48)58-18-10-13-27-19-32-33(21-35(27)56-3)44-37(57-5-2)22-36(32)59-30/h4,19,21-22,26,28-31,34,38H,1,5-18,20,23-25H2,2-3H3,(H,45,53)(H,46,50)(H,47,52)/t28-,29+,30-,34+,38+,43-/m1/s1	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of HCV genotype 1b BK NS3/4A protease A156V mutant expressed in Escherichia coli incubated for 30 mins by time-resolved fluorescence assay				Bioorg Med Chem Lett 22: 7207-13 (2012) Article DOI: 10.1016/j.bmcl.2012.09.061 BindingDB Entry DOI: 10.7270/Q28D0041
					More data for this Ligand-Target Pair