Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM50486106'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepacivirus C)	BDBM50486106 (CHEMBL2203878) Show SMILES [H][C@@]12CCC(C1)CCCc1cc3c(O[C@]4([H])C[C@H](N(C4)C(=O)[C@@H](NC(=O)O2)C2CCCC2)C(=O)N[C@@]2(C[C@H]2C=C)C(=O)NS(=O)(=O)C2CC2)cc(OCC)nc3cc1OC |r| Show InChI InChI=1S/C42H55N5O10S/c1-4-27-22-42(27,40(50)46-58(52,53)30-15-16-30)45-38(48)33-19-29-23-47(33)39(49)37(25-10-6-7-11-25)44-41(51)57-28-14-13-24(17-28)9-8-12-26-18-31-32(20-34(26)54-3)43-36(55-5-2)21-35(31)56-29/h4,18,20-21,24-25,27-30,33,37H,1,5-17,19,22-23H2,2-3H3,(H,44,51)(H,45,48)(H,46,50)/t24?,27-,28-,29-,33+,37+,42-/m1/s1	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of HCV genotype 1b BK NS3/4A protease A156T mutant expressed in Escherichia coli incubated for 30 mins by time-resolved fluorescence assay				Bioorg Med Chem Lett 22: 7207-13 (2012) Article DOI: 10.1016/j.bmcl.2012.09.061 BindingDB Entry DOI: 10.7270/Q28D0041
					More data for this Ligand-Target Pair
Genome polyprotein (Hepacivirus C)	BDBM50486106 (CHEMBL2203878) Show SMILES [H][C@@]12CCC(C1)CCCc1cc3c(O[C@]4([H])C[C@H](N(C4)C(=O)[C@@H](NC(=O)O2)C2CCCC2)C(=O)N[C@@]2(C[C@H]2C=C)C(=O)NS(=O)(=O)C2CC2)cc(OCC)nc3cc1OC |r| Show InChI InChI=1S/C42H55N5O10S/c1-4-27-22-42(27,40(50)46-58(52,53)30-15-16-30)45-38(48)33-19-29-23-47(33)39(49)37(25-10-6-7-11-25)44-41(51)57-28-14-13-24(17-28)9-8-12-26-18-31-32(20-34(26)54-3)43-36(55-5-2)21-35(31)56-29/h4,18,20-21,24-25,27-30,33,37H,1,5-17,19,22-23H2,2-3H3,(H,44,51)(H,45,48)(H,46,50)/t24?,27-,28-,29-,33+,37+,42-/m1/s1	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of HCV genotype 1b BK NS3/4A protease A156V mutant expressed in Escherichia coli incubated for 30 mins by time-resolved fluorescence assay				Bioorg Med Chem Lett 22: 7207-13 (2012) Article DOI: 10.1016/j.bmcl.2012.09.061 BindingDB Entry DOI: 10.7270/Q28D0041
					More data for this Ligand-Target Pair