Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Genome polyprotein [1027-1711]' and Ligand = 'BDBM235845'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein [1027-1711] (Hepatitis C virus genotype 1a (strain H77) (HCV))	BDBM235845 (US9364482, 19) Show SMILES CNC(=O)c1c(oc2cc(N(C)S(C)(=O)=O)c(cc12)-c1cnc2NCN(Cc3ccc(F)cc3)C(=O)c2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C32H27F2N5O5S/c1-35-31(40)28-24-13-23(26(38(2)45(3,42)43)14-27(24)44-29(28)19-6-10-22(34)11-7-19)20-12-25-30(36-15-20)37-17-39(32(25)41)16-18-4-8-21(33)9-5-18/h4-15H,16-17H2,1-3H3,(H,35,40)(H,36,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...				US Patent US9364482 (2016) BindingDB Entry DOI: 10.7270/Q2TT4PVB
					More data for this Ligand-Target Pair
Genome polyprotein [1027-1711] (Hepatitis C virus genotype 1b (isolate BK) (HCV))	BDBM235845 (US9364482, 19) Show SMILES CNC(=O)c1c(oc2cc(N(C)S(C)(=O)=O)c(cc12)-c1cnc2NCN(Cc3ccc(F)cc3)C(=O)c2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C32H27F2N5O5S/c1-35-31(40)28-24-13-23(26(38(2)45(3,42)43)14-27(24)44-29(28)19-6-10-22(34)11-7-19)20-12-25-30(36-15-20)37-17-39(32(25)41)16-18-4-8-21(33)9-5-18/h4-15H,16-17H2,1-3H3,(H,35,40)(H,36,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.75	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...				US Patent US9364482 (2016) BindingDB Entry DOI: 10.7270/Q2TT4PVB
					More data for this Ligand-Target Pair