Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Genome polyprotein [1027-1711]' and Ligand = 'BDBM235887'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein [1027-1711] (Hepatitis C virus genotype 1a (strain H77) (HCV))	BDBM235887 (US9364482, 68) Show SMILES CNC(=O)c1c(oc2cc(N(C)S(C)(=O)=O)c(cc12)-c1ccc2nc(C)n(Cc3ccc(F)cc3)c(=O)c2n1)-c1ccc(F)cc1 Show InChI InChI=1S/C33H27F2N5O5S/c1-18-37-26-14-13-25(38-30(26)33(42)40(18)17-19-5-9-21(34)10-6-19)23-15-24-28(16-27(23)39(3)46(4,43)44)45-31(29(24)32(41)36-2)20-7-11-22(35)12-8-20/h5-16H,17H2,1-4H3,(H,36,41)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...				US Patent US9364482 (2016) BindingDB Entry DOI: 10.7270/Q2TT4PVB
					More data for this Ligand-Target Pair
Genome polyprotein [1027-1711] (Hepatitis C virus genotype 1b (isolate BK) (HCV))	BDBM235887 (US9364482, 68) Show SMILES CNC(=O)c1c(oc2cc(N(C)S(C)(=O)=O)c(cc12)-c1ccc2nc(C)n(Cc3ccc(F)cc3)c(=O)c2n1)-c1ccc(F)cc1 Show InChI InChI=1S/C33H27F2N5O5S/c1-18-37-26-14-13-25(38-30(26)33(42)40(18)17-19-5-9-21(34)10-6-19)23-15-24-28(16-27(23)39(3)46(4,43)44)45-31(29(24)32(41)36-2)20-7-11-22(35)12-8-20/h5-16H,17H2,1-4H3,(H,36,41)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.24	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...				US Patent US9364482 (2016) BindingDB Entry DOI: 10.7270/Q2TT4PVB
					More data for this Ligand-Target Pair