Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Genome polyprotein [1027-3010]' and Ligand = 'BDBM243465'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein [1027-3010] (Hepatitis C virus genotype 1b (strain HC-J4) (HCV))	BDBM243465 (US9427440, 8) Show SMILES COc1ccc2-c3c(C4CCCCC4)c4ccc5cc4n3C[C@]3(C[C@H]3c2c1)C(=O)N(C)CCOCCN(C)S(=O)(=O)NC5=O |r| Show InChI InChI=1S/C33H40N4O6S/c1-35-13-15-43-16-14-36(2)44(40,41)34-31(38)22-9-11-25-28(17-22)37-20-33(32(35)39)19-27(33)26-18-23(42-3)10-12-24(26)30(37)29(25)21-7-5-4-6-8-21/h9-12,17-18,21,27H,4-8,13-16,19-20H2,1-3H3,(H,34,38)/t27-,33-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
Janssen Sciences Ireland UC US Patent					Assay Description The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...				US Patent US9427440 (2016) BindingDB Entry DOI: 10.7270/Q2DN43Z6
					More data for this Ligand-Target Pair