Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Genome polyprotein [1027-3010]' and Ligand = 'BDBM243475'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein [1027-3010] (Hepatitis C virus genotype 1b (strain HC-J4) (HCV))	BDBM243475 (US9427440, 23) Show SMILES COc1ccc2-c3c(C4CCCCC4)c4ccc5cc4n3CC(=Cc2c1)C(=O)NCCN(C)CCNS(=O)(=O)NC5=O |c:25| Show InChI InChI=1S/C31H37N5O5S/c1-35-14-12-32-30(37)23-16-22-17-24(41-2)9-11-25(22)29-28(20-6-4-3-5-7-20)26-10-8-21(18-27(26)36(29)19-23)31(38)34-42(39,40)33-13-15-35/h8-11,16-18,20,33H,3-7,12-15,19H2,1-2H3,(H,32,37)(H,34,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	470	n/a	n/a	n/a	n/a
Janssen Sciences Ireland UC US Patent					Assay Description The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...				US Patent US9427440 (2016) BindingDB Entry DOI: 10.7270/Q2DN43Z6
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