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Found 1 hit Enz. Inhib. hit(s) with Target = 'Genome polyprotein [1658-1692]' and Ligand = 'BDBM92629'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Genome polyprotein [1658-1692]


(Hepatitis C virus)		BDBM92629
PNG
((3S)-3-{[(1R)-1-(4-chloro-2-fluoro-3-phenoxyphenyl...)
Show SMILES CC[C@@H](N[C@@H](C)CC(N)=O)c1ccc(Cl)c(Oc2ccccc2)c1F |r|
Show InChI InChI=1S/C19H22ClFN2O2/c1-3-16(23-12(2)11-17(22)24)14-9-10-15(20)19(18(14)21)25-13-7-5-4-6-8-13/h4-10,12,16,23H,3,11H2,1-2H3,(H2,22,24)/t12-,16+/m0/s1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 100 62n/an/an/an/a25



Astex Pharmaceuticals



Assay Description
The protease activity of the full-length NS3-NS4a and the protease domain were measured using a FRET-based assay using a peptide substrate derived fr...

Nat Chem Biol 8: 920-5 (2012)


Article DOI: 10.1038/nchembio.1081
BindingDB Entry DOI: 10.7270/Q26Q1VVN
More data for this
Ligand-Target Pair