Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Genome polyprotein [192-746]' and Ligand = 'BDBM245445'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein [192-746] (Hepatitis C virus genotype 1b (isolate Con1) (HCV))	BDBM245445 (US9428469, 27) Show SMILES CS(=O)(=O)N1CCC(CC1)Nc1nc(Nc2cc(Cl)cc(Cl)c2)n[nH]1 Show InChI InChI=1S/C14H18Cl2N6O2S/c1-25(23,24)22-4-2-11(3-5-22)17-13-19-14(21-20-13)18-12-7-9(15)6-10(16)8-12/h6-8,11H,2-5H2,1H3,(H3,17,18,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5.96E+4	n/a	n/a	n/a	37
HOFFMANN-LA ROCHE US Patent					Assay Description Huh7-high CD81 cells were plated at a cell density of 8000 cells per well in 96 well plates (Perkin Elmer, cat #6005660). Cells were plated in 100 &m...				US Patent US9428469 (2016) BindingDB Entry DOI: 10.7270/Q21G0K6G
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