Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Genome polyprotein [2420-3010]' and Ligand = 'BDBM241875'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (isolate BK) (HCV))	BDBM241875 (US9416154, 18) Show SMILES CCOC(=O)[C@H](C)NP(=O)(OC(C)[C@H]1O[C@@H](n2ccc3c(N)ncnc23)[C@](C)(F)[C@@H]1O)Oc1cccc2ccccc12 |r| Show InChI InChI=1S/C28H33FN5O7P/c1-5-38-26(36)16(2)33-42(37,41-21-12-8-10-18-9-6-7-11-19(18)21)40-17(3)22-23(35)28(4,29)27(39-22)34-14-13-20-24(30)31-15-32-25(20)34/h6-17,22-23,27,35H,5H2,1-4H3,(H,33,37)(H2,30,31,32)/t16-,17?,22+,23+,27+,28+,42?/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	7.3	25
Merck Sharp & Dohme Corp. US Patent					Assay Description The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...				US Patent US9416154 (2016) BindingDB Entry DOI: 10.7270/Q2KK99PV
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