Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Genome polyprotein [S283T]' and Ligand = 'BDBM347259'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein [S283T] (Hepatitis C virus genotype 1b (isolate Japanese) (...)	BDBM347259 (US10202411, Compound 302) Show SMILES O[C@@H]1[C@H](CF)[C@@H](COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)O[C@H]1n1ccc(=O)[nH]c1=O |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	n/a	n/a
IDENIX PHARMACEUTICALS LLC US Patent					Assay Description Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...				US Patent US10202411 (2019) BindingDB Entry DOI: 10.7270/Q2RX9F67
					More data for this Ligand-Target Pair