Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50061453'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50061453 (1-[(2R,3R)-3-(2-Chloro-thiophen-3-ylmethoxy)-2,3-d...) Show SMILES Clc1sccc1CO[C@H]1[C@@H](Cn2ccnc2)Sc2c1ccc1ccccc21 Show InChI InChI=1S/C21H17ClN2OS2/c22-21-15(7-10-26-21)12-25-19-17-6-5-14-3-1-2-4-16(14)20(17)27-18(19)11-24-9-8-23-13-24/h1-10,13,18-19H,11-12H2/t18-,19-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against Geranylgeranyl transferase type I				J Med Chem 40: 4103-12 (1998) Article DOI: 10.1021/jm970291v BindingDB Entry DOI: 10.7270/Q2T152R0
					More data for this Ligand-Target Pair