BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50076130'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha


(Homo sapiens (Human))		BDBM50076130
PNG
((S)-2-(4-{[(1H-Imidazol-4-ylmethyl)-amino]-methyl}...)
Show SMILES CC(C)C[C@H](NC(=O)c1ccc(CNCc2cnc[nH]2)cc1-c1cccc2ccccc12)C(O)=O
Show InChI InChI=1S/C28H30N4O3/c1-18(2)12-26(28(34)35)32-27(33)24-11-10-19(14-29-15-21-16-30-17-31-21)13-25(24)23-9-5-7-20-6-3-4-8-22(20)23/h3-11,13,16-18,26,29H,12,14-15H2,1-2H3,(H,30,31)(H,32,33)(H,34,35)/t26-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 44n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]-GGPP incorporation into H-Ras-CVLL by Geranylgeranyl transferase type I

J Med Chem 42: 1333-40 (1999)


Article DOI: 10.1021/jm9900873
BindingDB Entry DOI: 10.7270/Q28G8JW7
More data for this
Ligand-Target Pair