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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50076133'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha


(Homo sapiens (Human))		BDBM50076133
PNG
((S)-2-({5-[(1H-Imidazol-4-ylmethyl)-amino]-3',5'-d...)
Show SMILES CC(C)C[C@H](NC(=O)c1ccc(NCc2cnc[nH]2)cc1-c1cc(C)cc(C)c1)C(O)=O
Show InChI InChI=1S/C25H30N4O3/c1-15(2)7-23(25(31)32)29-24(30)21-6-5-19(27-13-20-12-26-14-28-20)11-22(21)18-9-16(3)8-17(4)10-18/h5-6,8-12,14-15,23,27H,7,13H2,1-4H3,(H,26,28)(H,29,30)(H,31,32)/t23-/m0/s1
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KEGG

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Article
PubMed
n/an/a 150n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]-GGPP incorporation into H-Ras-CVLL by Geranylgeranyl transferase type I

J Med Chem 42: 1333-40 (1999)


Article DOI: 10.1021/jm9900873
BindingDB Entry DOI: 10.7270/Q28G8JW7
More data for this
Ligand-Target Pair