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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50076145'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha


(Homo sapiens (Human))		BDBM50076145
PNG
((S)-4-Methyl-2-{2-naphthalen-1-yl-4-[(pyridin-4-yl...)
Show SMILES CC(C)C[C@H](NC(=O)c1ccc(NCc2ccncc2)cc1-c1cccc2ccccc12)C(O)=O
Show InChI InChI=1S/C29H29N3O3/c1-19(2)16-27(29(34)35)32-28(33)25-11-10-22(31-18-20-12-14-30-15-13-20)17-26(25)24-9-5-7-21-6-3-4-8-23(21)24/h3-15,17,19,27,31H,16,18H2,1-2H3,(H,32,33)(H,34,35)/t27-/m0/s1
PDB

KEGG

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Similars
Article
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
In vitro inhibition of [3H]-GGPP incorporation into H-Ras-CVLL by Geranylgeranyl transferase type I

J Med Chem 42: 1333-40 (1999)


Article DOI: 10.1021/jm9900873
BindingDB Entry DOI: 10.7270/Q28G8JW7
More data for this
Ligand-Target Pair