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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50108057'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha


(Homo sapiens (Human))		BDBM50108057
PNG
(4'-[(3H-Imidazol-4-ylmethyl)-amino]-[1,1';2',1'']t...)
Show SMILES OC(=O)c1cccc(c1)-c1ccc(NCc2cnc[nH]2)cc1-c1ccccc1
Show InChI InChI=1S/C23H19N3O2/c27-23(28)18-8-4-7-17(11-18)21-10-9-19(25-14-20-13-24-15-26-20)12-22(21)16-5-2-1-3-6-16/h1-13,15,25H,14H2,(H,24,26)(H,27,28)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
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antibodypedia
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of partially purified Geranylgeranyl transferase type I (GGTase-I) from human Burkitt lymphoma (Daudi) cells

J Med Chem 45: 177-88 (2001)


BindingDB Entry DOI: 10.7270/Q22F7MQ7
More data for this
Ligand-Target Pair