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Found 1 hit Enz. Inhib. hit(s) with Target = 'Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50126330'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha


(Bos taurus (bovine))		BDBM50126330
PNG
(5-[(3-Cyano-benzyl)-(3-methyl-3H-imidazol-4-ylmeth...)
Show SMILES Cc1ccccc1-c1cc(ccc1C#N)N(Cc1cncn1C)Cc1cccc(c1)C#N
Show InChI InChI=1S/C27H23N5/c1-20-6-3-4-9-26(20)27-13-24(11-10-23(27)15-29)32(18-25-16-30-19-31(25)2)17-22-8-5-7-21(12-22)14-28/h3-13,16,19H,17-18H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.20E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against farnesyltransferase (FTase)

Bioorg Med Chem Lett 13: 1367-71 (2003)


BindingDB Entry DOI: 10.7270/Q20K27ZP
More data for this
Ligand-Target Pair