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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50134559'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha


(Homo sapiens (Human))		BDBM50134559
PNG
(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Show SMILES Cn1cncc1C(OCc1ccc(cc1C#Cc1ccc(cc1)[N+]([O-])=O)C#N)c1ccc(cc1)C#N
Show InChI InChI=1S/C28H19N5O3/c1-32-19-31-17-27(32)28(23-8-3-21(15-29)4-9-23)36-18-25-11-5-22(16-30)14-24(25)10-2-20-6-12-26(13-7-20)33(34)35/h3-9,11-14,17,19,28H,18H2,1H3
PDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 150n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibition of the human Geranylgeranyl transferase-catalyzed incorporation of [3H]-GGPP into biotinylated peptide corresponding to the C-ter...

Bioorg Med Chem Lett 13: 3821-5 (2003)


BindingDB Entry DOI: 10.7270/Q2319V9P
More data for this
Ligand-Target Pair