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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50134565'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha


(Homo sapiens (Human))		BDBM50134565
PNG
(4-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Show SMILES CCC\C=C\C=C\c1cc(ccc1COC(c1cncn1C)c1ccc(cc1)C#N)C#N
Show InChI InChI=1S/C27H26N4O/c1-3-4-5-6-7-8-24-15-22(17-29)11-14-25(24)19-32-27(26-18-30-20-31(26)2)23-12-9-21(16-28)10-13-23/h5-15,18,20,27H,3-4,19H2,1-2H3/b6-5+,8-7+
PDB

KEGG

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PC cid
PC sid
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Similars
PubMed
n/an/a 220n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibition of the human Geranylgeranyl transferase-catalyzed incorporation of [3H]-GGPP into biotinylated peptide corresponding to the C-ter...

Bioorg Med Chem Lett 13: 3821-5 (2003)


BindingDB Entry DOI: 10.7270/Q2319V9P
More data for this
Ligand-Target Pair