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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50135387'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha


(Homo sapiens (Human))		BDBM50135387
PNG
(6-[(3'-Chloro-6-cyano-biphenyl-3-yl)-(3-methyl-3H-...)
Show SMILES Cn1cncc1C(OCc1c(cc(C#N)c(=O)n1C)-c1cc(Cl)cc(Cl)c1)c1ccc(C#N)c(c1)-c1cccc(Cl)c1
Show InChI InChI=1S/C32H22Cl3N5O2/c1-39-18-38-16-29(39)31(20-6-7-21(14-36)27(11-20)19-4-3-5-24(33)8-19)42-17-30-28(12-23(15-37)32(41)40(30)2)22-9-25(34)13-26(35)10-22/h3-13,16,18,31H,17H2,1-2H3
PDB

KEGG

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PC cid
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Similars
PubMed
n/an/a 120n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibitory activity of the compound against Geranylgeranyl transferase type I

Bioorg Med Chem Lett 13: 4001-5 (2003)


BindingDB Entry DOI: 10.7270/Q2H41QVX
More data for this
Ligand-Target Pair