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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Geranylgeranyl transferase type-1 subunit beta' and Ligand = 'BDBM50127308'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Geranylgeranyl transferase type-1 subunit beta


(Homo sapiens (Human))		BDBM50127308
PNG
(5-[(4-Cyano-2-naphthalen-1-yl-benzyloxy)-(3-methyl...)
Show SMILES Cn1cncc1C(OCc1ccc(cc1-c1cccc2ccccc12)C#N)c1ccc(nc1)C#N
Show InChI InChI=1S/C29H21N5O/c1-34-19-32-17-28(34)29(22-11-12-24(15-31)33-16-22)35-18-23-10-9-20(14-30)13-27(23)26-8-4-6-21-5-2-3-7-25(21)26/h2-13,16-17,19,29H,18H2,1H3
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n/an/a>10n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of transfer of [3H]-FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine GGTase-I

Bioorg Med Chem Lett 13: 1571-4 (2003)


BindingDB Entry DOI: 10.7270/Q27080TK
More data for this
Ligand-Target Pair