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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Geranylgeranyl transferase type-1 subunit beta' and Ligand = 'BDBM50127325'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Geranylgeranyl transferase type-1 subunit beta


(Homo sapiens (Human))		BDBM50127325
PNG
(5-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Show SMILES Cn1cncc1C(OCc1ccc(nc1N1CCOCC1)C#N)c1ccc(cc1)C#N
Show InChI InChI=1S/C23H22N6O2/c1-28-16-26-14-21(28)22(18-4-2-17(12-24)3-5-18)31-15-19-6-7-20(13-25)27-23(19)29-8-10-30-11-9-29/h2-7,14,16,22H,8-11,15H2,1H3
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n/an/a>10n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of transfer of [3H]-FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine GGTase-I

Bioorg Med Chem Lett 13: 1571-4 (2003)


BindingDB Entry DOI: 10.7270/Q27080TK
More data for this
Ligand-Target Pair