Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Geranylgeranyl transferase type-1 subunit beta' and Ligand = 'BDBM50481907'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Geranylgeranyl transferase type-1 subunit beta (Rattus norvegicus)	BDBM50481907 (CHEMBL1075810) Show SMILES OC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)[C@H](Cc1cn(cn1)C(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)c1coc(n1)-c1ccccc1 |r| Show InChI InChI=1S/C43H38N8O6/c52-38(48-36(42(55)56)21-33-23-44-27-46-33)24-45-39(53)35(49-40(54)37-26-57-41(50-37)29-13-5-1-6-14-29)22-34-25-51(28-47-34)43(30-15-7-2-8-16-30,31-17-9-3-10-18-31)32-19-11-4-12-20-32/h1-20,23,25-28,35-36H,21-22,24H2,(H,44,46)(H,45,53)(H,48,52)(H,49,54)(H,55,56)/t35-,36-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Inhibition of rat recombinant GGTase-1 by SDS-PAGE end point assay				J Med Chem 52: 8025-37 (2009) Article DOI: 10.1021/jm901117d BindingDB Entry DOI: 10.7270/Q25X2CS3
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