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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ghrelin O-acyltransferase' and Ligand = 'BDBM396189'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ghrelin O-acyltransferase


(Homo sapiens (Human))		BDBM396189
PNG
(6-[5-Bromo-6-(2,2-difluoro-ethoxy)-pyridin-2-yl me...)
Show SMILES Cc1nc2nonc2c(N)c1Cc1ccc(Br)c(OCC(F)F)n1
Show InChI InChI=1S/C14H12BrF2N5O2/c1-6-8(11(18)12-13(19-6)22-24-21-12)4-7-2-3-9(15)14(20-7)23-5-10(16)17/h2-3,10H,4-5,18H2,1H3
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 0.0580n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...

Bioorg Med Chem Lett 17: 4664-9 (2007)


BindingDB Entry DOI: 10.7270/Q2VH5R5S
More data for this
Ligand-Target Pair