Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glucagon receptor' and Ligand = 'BDBM235137'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM235137 (US9359339, 27) Show SMILES OC(=O)CCNC(=O)c1ccc(cc1)[C@@H](CCC(F)(F)F)C(c1csc2c(cc(Cl)cc12)C#N)c1ccc(Cl)cc1 Show InChI InChI=1S/C30H23Cl2F3N2O3S/c31-21-7-5-18(6-8-21)27(25-16-41-28-20(15-36)13-22(32)14-24(25)28)23(9-11-30(33,34)35)17-1-3-19(4-2-17)29(40)37-12-10-26(38)39/h1-8,13-14,16,23,27H,9-12H2,(H,37,40)(H,38,39)/t23-,27?/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	7.5	25
Merck Sharp & Dohme Corp. US Patent					Assay Description A stable CHO (Chinese hamster ovary) cell line expressing cloned human glucagon receptor was maintained as described (Chicchi, et. al. J Biol Chem 27...				US Patent US9359339 (2016) BindingDB Entry DOI: 10.7270/Q2FQ9VHC
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