Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glucagon receptor' and Ligand = 'BDBM50120320'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM50120320 (CHEMBL3616589) Show SMILES CCCC(c1ccc(cc1)C(=O)NCCC(O)=O)n1cc(-c2cc(ccc2OC)C(F)(F)F)c2ccc(nc12)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C36H31F6N3O5/c1-3-4-30(22-5-7-23(8-6-22)34(48)43-18-17-32(46)47)45-20-28(27-19-24(35(37,38)39)11-16-31(27)49-2)26-14-15-29(44-33(26)45)21-9-12-25(13-10-21)50-36(40,41)42/h5-16,19-20,30H,3-4,17-18H2,1-2H3,(H,43,48)(H,46,47)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 25: 4143-7 (2015) Article DOI: 10.1016/j.bmcl.2015.08.015 BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50120320 (CHEMBL3616589) Show SMILES CCCC(c1ccc(cc1)C(=O)NCCC(O)=O)n1cc(-c2cc(ccc2OC)C(F)(F)F)c2ccc(nc12)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C36H31F6N3O5/c1-3-4-30(22-5-7-23(8-6-22)34(48)43-18-17-32(46)47)45-20-28(27-19-24(35(37,38)39)11-16-31(27)49-2)26-14-15-29(44-33(26)45)21-9-12-25(13-10-21)50-36(40,41)42/h5-16,19-20,30H,3-4,17-18H2,1-2H3,(H,43,48)(H,46,47)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity against human glucagon receptor expressed in CHO cells assessed as reduction in glucagon-induced cAMP production				Bioorg Med Chem Lett 25: 4143-7 (2015) Article DOI: 10.1016/j.bmcl.2015.08.015 BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair