Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glucagon receptor' and Ligand = 'BDBM50120371'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM50120371 (CHEMBL3616698) Show SMILES CCCCC(c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(-c2cc(ccc2OC)C(F)(F)F)c2ccc(cc12)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C36H31F6N3O4/c1-3-4-5-29(20-6-8-21(9-7-20)35(48)43-15-14-32(46)47)45-30-18-22(23-16-27(37)33(39)28(38)17-23)10-12-25(30)34(44-45)26-19-24(36(40,41)42)11-13-31(26)49-2/h6-13,16-19,29H,3-5,14-15H2,1-2H3,(H,43,48)(H,46,47)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]glucagon from human glucagon receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 25: 4143-7 (2015) Article DOI: 10.1016/j.bmcl.2015.08.015 BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50120371 (CHEMBL3616698) Show SMILES CCCCC(c1ccc(cc1)C(=O)NCCC(O)=O)n1nc(-c2cc(ccc2OC)C(F)(F)F)c2ccc(cc12)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C36H31F6N3O4/c1-3-4-5-29(20-6-8-21(9-7-20)35(48)43-15-14-32(46)47)45-30-18-22(23-16-27(37)33(39)28(38)17-23)10-12-25(30)34(44-45)26-19-24(36(40,41)42)11-13-31(26)49-2/h6-13,16-19,29H,3-5,14-15H2,1-2H3,(H,43,48)(H,46,47)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity against human glucagon receptor expressed in CHO cells assessed as reduction in glucagon-induced cAMP production				Bioorg Med Chem Lett 25: 4143-7 (2015) Article DOI: 10.1016/j.bmcl.2015.08.015 BindingDB Entry DOI: 10.7270/Q23F4RGX
					More data for this Ligand-Target Pair