Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glucagon-like peptide 1 receptor' and Ligand = 'BDBM189948'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon-like peptide 1 receptor (Homo sapiens (Human))	BDBM189948 (US9175003, 60) Show SMILES Cc1nc(N)sc1S(=O)(=O)N1Cc2cc3O[C@@H](COc3cc2C[C@H]1C(=O)N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)C(O)=O)c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1 |r| Show InChI InChI=1S/C45H37Cl2N5O8S2/c1-25-44(61-45(49)50-25)62(56,57)52-22-33-20-40-39(59-24-41(60-40)31-11-13-34(14-12-31)58-23-28-6-15-35(46)36(47)16-28)19-32(33)18-38(52)42(53)51-37(43(54)55)17-26-2-7-29(8-3-26)30-9-4-27(21-48)5-10-30/h2-16,19-20,37-38,41H,17-18,22-24H2,1H3,(H2,49,50)(H,51,53)(H,54,55)/t37-,38-,41-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	109	n/a	n/a	n/a	n/a
vTv Therapeutics LLC US Patent					Assay Description The efficacy of GLP-1 receptor agonists was studied in a cAMP functional assay using HEK-293 Cells expressing the cloned human GLP-1 receptor. GLP-1-...				US Patent US9175003 (2015) BindingDB Entry DOI: 10.7270/Q27943FG
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