Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glucagon-like peptide 1 receptor' and Ligand = 'BDBM189995'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon-like peptide 1 receptor (Homo sapiens (Human))	BDBM189995 (US9175003, 154) Show SMILES Cc1nccc(c1C)-c1ccc(C[C@H](NC(=O)[C@@H]2Cc3cc4OC[C@@H](Oc4cc3CN2C(=O)C2CCCC2)c2ccc(OCc3ccc(Cl)c(Cl)c3)cc2)C(O)=O)cc1 |r| Show InChI InChI=1S/C47H45Cl2N3O7/c1-27-28(2)50-18-17-37(27)31-10-7-29(8-11-31)20-40(47(55)56)51-45(53)41-21-34-22-42-43(23-35(34)24-52(41)46(54)33-5-3-4-6-33)59-44(26-58-42)32-12-14-36(15-13-32)57-25-30-9-16-38(48)39(49)19-30/h7-19,22-23,33,40-41,44H,3-6,20-21,24-26H2,1-2H3,(H,51,53)(H,55,56)/t40-,41-,44+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	108	n/a	n/a	n/a	n/a
vTv Therapeutics LLC US Patent					Assay Description The efficacy of GLP-1 receptor agonists was studied in a cAMP functional assay using HEK-293 Cells expressing the cloned human GLP-1 receptor. GLP-1-...				US Patent US9175003 (2015) BindingDB Entry DOI: 10.7270/Q27943FG
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