Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glucagon-like peptide 1 receptor' and Ligand = 'BDBM189999'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon-like peptide 1 receptor (Homo sapiens (Human))	BDBM189999 (US9175003, 158) Show SMILES Cc1ccc(cc1)C(=O)N1Cc2cc3O[C@H](COc3cc2C[C@H]1C(=O)N[C@@H](Cc1ccc(cc1)-c1ccnc(C)c1C)C(O)=O)c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1 |r| Show InChI InChI=1S/C49H43Cl2N3O7/c1-28-4-9-35(10-5-28)48(56)54-25-37-24-45-44(60-27-46(61-45)34-13-15-38(16-14-34)59-26-32-8-17-40(50)41(51)20-32)23-36(37)22-43(54)47(55)53-42(49(57)58)21-31-6-11-33(12-7-31)39-18-19-52-30(3)29(39)2/h4-20,23-24,42-43,46H,21-22,25-27H2,1-3H3,(H,53,55)(H,57,58)/t42-,43-,46+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	146	n/a	n/a	n/a	n/a
vTv Therapeutics LLC US Patent					Assay Description The efficacy of GLP-1 receptor agonists was studied in a cAMP functional assay using HEK-293 Cells expressing the cloned human GLP-1 receptor. GLP-1-...				US Patent US9175003 (2015) BindingDB Entry DOI: 10.7270/Q27943FG
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