Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glucagon-like peptide 1 receptor' and Ligand = 'BDBM190070'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon-like peptide 1 receptor (Homo sapiens (Human))	BDBM190070 (US9175003, 255) Show SMILES Cc1nccc(c1C)-c1ccc(C[C@H](NC(=O)[C@@H]2Cc3cc4OC[C@@H](Oc4cc3CN2C(=O)Nc2cc(F)cc(F)c2)c2ccc(OCc3ccc(Cl)c(Cl)c3)cc2)C(O)=O)cc1 |r| Show InChI InChI=1S/C48H40Cl2F2N4O7/c1-26-27(2)53-14-13-38(26)30-6-3-28(4-7-30)16-41(47(58)59)55-46(57)42-17-32-18-43-44(19-33(32)23-56(42)48(60)54-36-21-34(51)20-35(52)22-36)63-45(25-62-43)31-8-10-37(11-9-31)61-24-29-5-12-39(49)40(50)15-29/h3-15,18-22,41-42,45H,16-17,23-25H2,1-2H3,(H,54,60)(H,55,57)(H,58,59)/t41-,42-,45+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	317	n/a	n/a	n/a	n/a
vTv Therapeutics LLC US Patent					Assay Description The efficacy of GLP-1 receptor agonists was studied in a cAMP functional assay using HEK-293 Cells expressing the cloned human GLP-1 receptor. GLP-1-...				US Patent US9175003 (2015) BindingDB Entry DOI: 10.7270/Q27943FG
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