Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glucagon-like peptide 1 receptor' and Ligand = 'BDBM349748'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon-like peptide 1 receptor (Homo sapiens (Human))	BDBM349748 (2-{[(2S)-4-{6-[(4-chloro-2-fluorobenzyl)oxy]pyridi...) Show SMILES C[C@H]1CN(CCN1Cc1nc2ccc(cc2n1Cc1ncco1)C(O)=O)c1cccc(OCc2ccc(Cl)cc2F)n1 Show InChI InChI=1S/C30H28ClFN6O4/c1-19-15-37(26-3-2-4-28(35-26)42-18-21-5-7-22(31)14-23(21)32)11-10-36(19)16-27-34-24-8-6-20(30(39)40)13-25(24)38(27)17-29-33-9-12-41-29/h2-9,12-14,19H,10-11,15-18H2,1H3,(H,39,40)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	33	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description GLP-1R-mediated agonist activity was determined with a cell-based functional assay utilizing an HTRF (Homogeneous Time-Resolved Fluorescence) cAMP de...				US Patent US10208019 (2019) BindingDB Entry DOI: 10.7270/Q2WH2S4X
					More data for this Ligand-Target Pair
Glucagon-like peptide 1 receptor (Homo sapiens (Human))	BDBM349748 (2-{[(2S)-4-{6-[(4-chloro-2-fluorobenzyl)oxy]pyridi...) Show SMILES C[C@H]1CN(CCN1Cc1nc2ccc(cc2n1Cc1ncco1)C(O)=O)c1cccc(OCc2ccc(Cl)cc2F)n1 Show InChI InChI=1S/C30H28ClFN6O4/c1-19-15-37(26-3-2-4-28(35-26)42-18-21-5-7-22(31)14-23(21)32)11-10-36(19)16-27-34-24-8-6-20(30(39)40)13-25(24)38(27)17-29-33-9-12-41-29/h2-9,12-14,19H,10-11,15-18H2,1H3,(H,39,40)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description GLP-1R-mediated agonist activity was determined with a cell-based functional assay utilizing an HTRF (Homogeneous Time-Resolved Fluorescence) cAMP de...				US Patent US10208019 (2019) BindingDB Entry DOI: 10.7270/Q2WH2S4X
					More data for this Ligand-Target Pair