Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glucagon-like peptide 1 receptor' and Ligand = 'BDBM50273771'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon-like peptide 1 receptor (Homo sapiens (Human))	BDBM50273771 (CHEMBL526164) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H]1CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCCCNC(=O)CC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O)C(C)C)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r| Show InChI InChI=1S/C151H223N41O47/c1-12-76(6)121(148(237)184-103(59-82-28-15-13-16-29-82)139(228)174-93-35-22-25-55-159-111(200)49-43-95(129(218)163-67-113(202)170-91(124(155)213)37-27-57-161-151(156)157)179-147(236)120(75(4)5)190-142(231)101(58-74(2)3)180-140(229)105(182-134(93)223)62-85-65-162-90-33-20-19-32-88(85)90)191-137(226)100(47-53-118(209)210)177-133(222)92(34-21-24-54-152)172-126(215)78(8)167-125(214)77(7)169-132(221)98(42-48-110(154)199)171-114(203)68-164-131(220)97(46-52-117(207)208)176-136(225)99-44-50-112(201)160-56-26-23-36-94(135(224)186-108(71-194)146(235)187-107(70-193)144(233)181-102(138(227)178-99)61-84-38-40-87(198)41-39-84)175-141(230)106(64-119(211)212)183-145(234)109(72-195)188-150(239)123(81(11)197)192-143(232)104(60-83-30-17-14-18-31-83)185-149(238)122(80(10)196)189-115(204)69-165-130(219)96(45-51-116(205)206)173-127(216)79(9)168-128(217)89(153)63-86-66-158-73-166-86/h13-20,28-33,38-41,65-66,73-81,89,91-109,120-123,162,193-198H,12,21-27,34-37,42-64,67-72,152-153H2,1-11H3,(H2,154,199)(H2,155,213)(H,158,166)(H,159,200)(H,160,201)(H,163,218)(H,164,220)(H,165,219)(H,167,214)(H,168,217)(H,169,221)(H,170,202)(H,171,203)(H,172,215)(H,173,216)(H,174,228)(H,175,230)(H,176,225)(H,177,222)(H,178,227)(H,179,236)(H,180,229)(H,181,233)(H,182,223)(H,183,234)(H,184,237)(H,185,238)(H,186,224)(H,187,235)(H,188,239)(H,189,204)(H,190,231)(H,191,226)(H,192,232)(H,205,206)(H,207,208)(H,209,210)(H,211,212)(H4,156,157,161)/t76-,77-,78-,79-,80+,81+,89-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,120-,121-,122-,123-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.00331	n/a	n/a	n/a	n/a
University of Texas at Dallas Curated by ChEMBL					Assay Description Activation of human GLP1R expressed in HEK293 cells assessed as effect on cAMP responsive element promoter driven luciferase expression				Bioorg Med Chem 16: 10106-12 (2008) Article DOI: 10.1016/j.bmc.2008.10.006 BindingDB Entry DOI: 10.7270/Q2B857ZT
					More data for this Ligand-Target Pair