Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM141383'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM141383 (US8916600, 17 | US9738632, Example 17) Show SMILES C[C@H](NC(=O)C(C)(F)F)[C@H](Oc1ccc2n(ncc2c1)-c1cccc(c1)C(=O)NCc1ccccc1)c1ccc2COCOc2c1 |r| Show InChI InChI=1S/C35H32F2N4O5/c1-22(40-34(43)35(2,36)37)32(24-11-12-26-20-44-21-45-31(26)17-24)46-29-13-14-30-27(16-29)19-39-41(30)28-10-6-9-25(15-28)33(42)38-18-23-7-4-3-5-8-23/h3-17,19,22,32H,18,20-21H2,1-2H3,(H,38,42)(H,40,43)/t22-,32-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.996	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB; Bayer Pharma Aktiengesellschaft US Patent					Assay Description In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...				US Patent US9738632 (2017) BindingDB Entry DOI: 10.7270/Q2057J12
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM141383 (US8916600, 17 | US9738632, Example 17) Show SMILES C[C@H](NC(=O)C(C)(F)F)[C@H](Oc1ccc2n(ncc2c1)-c1cccc(c1)C(=O)NCc1ccccc1)c1ccc2COCOc2c1 |r| Show InChI InChI=1S/C35H32F2N4O5/c1-22(40-34(43)35(2,36)37)32(24-11-12-26-20-44-21-45-31(26)17-24)46-29-13-14-30-27(16-29)19-39-41(30)28-10-6-9-25(15-28)33(42)38-18-23-7-4-3-5-8-23/h3-17,19,22,32H,18,20-21H2,1-2H3,(H,38,42)(H,40,43)/t22-,32-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.996	n/a	n/a	n/a	n/a	7.4	25
Astrazeneca AB; Bayer Pharma Aktiengesellschaft US Patent					Assay Description In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 uM. ...				US Patent US8916600 (2014) BindingDB Entry DOI: 10.7270/Q2WQ02HG
					More data for this Ligand-Target Pair