Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM381532'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM381532 (4-Chloro-1-(6-methoxy-pyrimidin- 4-ylmethyl)-3-met...) Show SMILES COc1cc(Cn2nc(C)c3c(Cl)c(cnc23)C(=O)Nc2ccc(cc2)C(F)(F)F)ncn1 Show InChI InChI=1S/C21H16ClF3N6O2/c1-11-17-18(22)15(20(32)29-13-5-3-12(4-6-13)21(23,24)25)8-26-19(17)31(30-11)9-14-7-16(33-2)28-10-27-14/h3-8,10H,9H2,1-2H3,(H,29,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description The assay was performed using H4 neuroglioma cells and using indirect immunofluorescence detection of the endogenous GR receptor. Fixative: 4% PFA. P...				J Med Chem 51: 5663-79 (2008) BindingDB Entry DOI: 10.7270/Q29P33Z7
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