Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50124600'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50124600 (5-Allyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza...) Show SMILES CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4cccc(C#N)c-34)c12 |t:1| Show InChI InChI=1S/C23H22N2O/c1-5-7-18-22-16(21-15(13-24)8-6-9-19(21)26-18)10-11-17-20(22)14(2)12-23(3,4)25-17/h5-6,8-12,18,25H,1,7H2,2-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells				J Med Chem 46: 1016-30 (2003) Article DOI: 10.1021/jm020335m BindingDB Entry DOI: 10.7270/Q2MP52NB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50124600 (5-Allyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza...) Show SMILES CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4cccc(C#N)c-34)c12 |t:1| Show InChI InChI=1S/C23H22N2O/c1-5-7-18-22-16(21-15(13-24)8-6-9-19(21)26-18)10-11-17-20(22)14(2)12-23(3,4)25-17/h5-6,8-12,18,25H,1,7H2,2-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity towards aldosterone receptor (Mineralocorticoid receptor)				J Med Chem 46: 1016-30 (2003) Article DOI: 10.1021/jm020335m BindingDB Entry DOI: 10.7270/Q2MP52NB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50124600 (5-Allyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza...) Show SMILES CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4cccc(C#N)c-34)c12 |t:1| Show InChI InChI=1S/C23H22N2O/c1-5-7-18-22-16(21-15(13-24)8-6-9-19(21)26-18)10-11-17-20(22)14(2)12-23(3,4)25-17/h5-6,8-12,18,25H,1,7H2,2-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	195	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Transcriptional repression in HepG2 cells expressing human glucocorticoid receptor				J Med Chem 46: 1016-30 (2003) Article DOI: 10.1021/jm020335m BindingDB Entry DOI: 10.7270/Q2MP52NB
					More data for this Ligand-Target Pair