Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50203181'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50203181 (CHEMBL3957844) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H23NO4S/c1-30-23-16-18-26(19-17-23)32(28,29)27(20-21-8-4-2-5-9-21)22-12-14-25(15-13-22)31-24-10-6-3-7-11-24/h2-19H,20H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Molecular and Cellular Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, 113-0032 Tokyo, Japan. Curated by ChEMBL					Assay Description Antagonist activity at human GRalpha expressed in HEK293 cells assessed as inhibition of dexamethasone-induced response after 24 hrs by luciferase re...				Bioorg Med Chem 25: 3461-3470 (2017) Article DOI: 10.1016/j.bmc.2017.04.032 BindingDB Entry DOI: 10.7270/Q2SF2ZK6
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