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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50203586'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucocorticoid receptor


(Homo sapiens (Human))		BDBM50203586
PNG
(CHEMBL400047 | diethyl {4-[(2R,10'S,11'S,15'S,17'R...)
Show SMILES CCOP(=O)(OCC)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@]22OCCC2=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:33,40|
Show InChI InChI=1S/C32H41O5P/c1-5-36-38(34,37-6-2)25-11-7-22(8-12-25)28-20-31(4)29(15-17-32(31)21(3)16-18-35-32)27-13-9-23-19-24(33)10-14-26(23)30(27)28/h7-8,11-12,19,27-29H,3,5-6,9-10,13-18,20H2,1-2,4H3/t27-,28+,29-,31-,32+/m0/s1
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Article
PubMed
 56.3n/an/an/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development L.L.C.

Curated by ChEMBL


Assay Description
Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of corticoid-induced transcription by glucocortic...

Bioorg Med Chem Lett 17: 1471-4 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.003
BindingDB Entry DOI: 10.7270/Q2PN96GJ
More data for this
Ligand-Target Pair