Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50334052'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334052 (5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-4-(...) Show SMILES CC(C)=CCC1(C)C(=O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |(32.68,-5.02,;31.14,-5.03,;30.36,-3.7,;30.38,-6.37,;28.84,-6.39,;28.08,-7.73,;27.3,-6.39,;29.42,-8.5,;30.75,-7.73,;29.42,-10.04,;30.18,-11.37,;30.9,-9.64,;28.08,-10.81,;26.76,-10.05,;25.43,-10.83,;25.43,-12.37,;24.09,-10.06,;24.09,-8.52,;25.42,-7.75,;25.41,-6.21,;26.75,-8.51,;22.76,-7.75,;22.76,-6.2,;21.42,-5.44,;20.1,-6.21,;20.09,-7.74,;18.94,-8.78,;19.56,-10.19,;21.1,-10.03,;21.43,-8.52,)| Show InChI InChI=1S/C26H29ClN2O/c1-15(2)10-12-26(6)20-21(27)19(18-9-7-8-17-11-13-28-23(17)18)14-16(3)22(20)29-25(4,5)24(26)30/h7-11,13-14,28-29H,12H2,1-6H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirus				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334052 (5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-4-(...) Show SMILES CC(C)=CCC1(C)C(=O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |(32.68,-5.02,;31.14,-5.03,;30.36,-3.7,;30.38,-6.37,;28.84,-6.39,;28.08,-7.73,;27.3,-6.39,;29.42,-8.5,;30.75,-7.73,;29.42,-10.04,;30.18,-11.37,;30.9,-9.64,;28.08,-10.81,;26.76,-10.05,;25.43,-10.83,;25.43,-12.37,;24.09,-10.06,;24.09,-8.52,;25.42,-7.75,;25.41,-6.21,;26.75,-8.51,;22.76,-7.75,;22.76,-6.2,;21.42,-5.44,;20.1,-6.21,;20.09,-7.74,;18.94,-8.78,;19.56,-10.19,;21.1,-10.03,;21.43,-8.52,)| Show InChI InChI=1S/C26H29ClN2O/c1-15(2)10-12-26(6)20-21(27)19(18-9-7-8-17-11-13-28-23(17)18)14-16(3)22(20)29-25(4,5)24(26)30/h7-11,13-14,28-29H,12H2,1-6H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor in TNFalpha/IL1beta-stimulated human HepG2 cells assessed as inhibition of NFkappaB-dependent E-s...				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334052 (5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-4-(...) Show SMILES CC(C)=CCC1(C)C(=O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |(32.68,-5.02,;31.14,-5.03,;30.36,-3.7,;30.38,-6.37,;28.84,-6.39,;28.08,-7.73,;27.3,-6.39,;29.42,-8.5,;30.75,-7.73,;29.42,-10.04,;30.18,-11.37,;30.9,-9.64,;28.08,-10.81,;26.76,-10.05,;25.43,-10.83,;25.43,-12.37,;24.09,-10.06,;24.09,-8.52,;25.42,-7.75,;25.41,-6.21,;26.75,-8.51,;22.76,-7.75,;22.76,-6.2,;21.42,-5.44,;20.1,-6.21,;20.09,-7.74,;18.94,-8.78,;19.56,-10.19,;21.1,-10.03,;21.43,-8.52,)| Show InChI InChI=1S/C26H29ClN2O/c1-15(2)10-12-26(6)20-21(27)19(18-9-7-8-17-11-13-28-23(17)18)14-16(3)22(20)29-25(4,5)24(26)30/h7-11,13-14,28-29H,12H2,1-6H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor in IL-1beta-stimulated human HepG2 cells assessed as inhibition of AP1 response element-induced I...				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334052 (5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-4-(...) Show SMILES CC(C)=CCC1(C)C(=O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |(32.68,-5.02,;31.14,-5.03,;30.36,-3.7,;30.38,-6.37,;28.84,-6.39,;28.08,-7.73,;27.3,-6.39,;29.42,-8.5,;30.75,-7.73,;29.42,-10.04,;30.18,-11.37,;30.9,-9.64,;28.08,-10.81,;26.76,-10.05,;25.43,-10.83,;25.43,-12.37,;24.09,-10.06,;24.09,-8.52,;25.42,-7.75,;25.41,-6.21,;26.75,-8.51,;22.76,-7.75,;22.76,-6.2,;21.42,-5.44,;20.1,-6.21,;20.09,-7.74,;18.94,-8.78,;19.56,-10.19,;21.1,-10.03,;21.43,-8.52,)| Show InChI InChI=1S/C26H29ClN2O/c1-15(2)10-12-26(6)20-21(27)19(18-9-7-8-17-11-13-28-23(17)18)14-16(3)22(20)29-25(4,5)24(26)30/h7-11,13-14,28-29H,12H2,1-6H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	215	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at glucocorticoid receptor in human HepG2 cells co-transfected with GRE assessed as transactivation activity by luciferase reporter ...				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair