Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50340667'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50340667 (5,7-difluoro-6-(1H-indol-7-yl)-2,2-dimethyl-2,3-di...) Show SMILES CC(C)(C)O\N=C1/CC(C)(C)Nc2cc(F)c(c(F)c12)-c1cccc2cc[nH]c12 |(1.19,-17.96,;-.14,-18.72,;-1.46,-17.95,;-.15,-17.18,;-.15,-20.26,;-1.48,-21.02,;-1.49,-22.55,;-.16,-23.34,;-.18,-24.88,;1.14,-24.1,;1.14,-25.65,;-1.52,-25.64,;-2.84,-24.86,;-4.17,-25.62,;-5.49,-24.85,;-6.82,-25.61,;-5.49,-23.31,;-4.16,-22.54,;-4.16,-21,;-2.83,-23.32,;-6.81,-22.53,;-6.81,-20.99,;-8.15,-20.21,;-9.48,-20.99,;-9.49,-22.53,;-10.63,-23.56,;-10.01,-24.97,;-8.47,-24.81,;-8.15,-23.3,)| Show InChI InChI=1S/C23H25F2N3O/c1-22(2,3)29-28-17-12-23(4,5)27-16-11-15(24)18(20(25)19(16)17)14-8-6-7-13-9-10-26-21(13)14/h6-11,26-27H,12H2,1-5H3/b28-17+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirus				Bioorg Med Chem Lett 21: 1654-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.104 BindingDB Entry DOI: 10.7270/Q21V5F8D
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50340667 (5,7-difluoro-6-(1H-indol-7-yl)-2,2-dimethyl-2,3-di...) Show SMILES CC(C)(C)O\N=C1/CC(C)(C)Nc2cc(F)c(c(F)c12)-c1cccc2cc[nH]c12 |(1.19,-17.96,;-.14,-18.72,;-1.46,-17.95,;-.15,-17.18,;-.15,-20.26,;-1.48,-21.02,;-1.49,-22.55,;-.16,-23.34,;-.18,-24.88,;1.14,-24.1,;1.14,-25.65,;-1.52,-25.64,;-2.84,-24.86,;-4.17,-25.62,;-5.49,-24.85,;-6.82,-25.61,;-5.49,-23.31,;-4.16,-22.54,;-4.16,-21,;-2.83,-23.32,;-6.81,-22.53,;-6.81,-20.99,;-8.15,-20.21,;-9.48,-20.99,;-9.49,-22.53,;-10.63,-23.56,;-10.01,-24.97,;-8.47,-24.81,;-8.15,-23.3,)| Show InChI InChI=1S/C23H25F2N3O/c1-22(2,3)29-28-17-12-23(4,5)27-16-11-15(24)18(20(25)19(16)17)14-8-6-7-13-9-10-26-21(13)14/h6-11,26-27H,12H2,1-5H3/b28-17+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor in human HepG2 cells assessed as inhibition of TNFalpha/IL1beta-stimulated NFkappaB-dependent E-s...				Bioorg Med Chem Lett 21: 1654-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.104 BindingDB Entry DOI: 10.7270/Q21V5F8D
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50340667 (5,7-difluoro-6-(1H-indol-7-yl)-2,2-dimethyl-2,3-di...) Show SMILES CC(C)(C)O\N=C1/CC(C)(C)Nc2cc(F)c(c(F)c12)-c1cccc2cc[nH]c12 |(1.19,-17.96,;-.14,-18.72,;-1.46,-17.95,;-.15,-17.18,;-.15,-20.26,;-1.48,-21.02,;-1.49,-22.55,;-.16,-23.34,;-.18,-24.88,;1.14,-24.1,;1.14,-25.65,;-1.52,-25.64,;-2.84,-24.86,;-4.17,-25.62,;-5.49,-24.85,;-6.82,-25.61,;-5.49,-23.31,;-4.16,-22.54,;-4.16,-21,;-2.83,-23.32,;-6.81,-22.53,;-6.81,-20.99,;-8.15,-20.21,;-9.48,-20.99,;-9.49,-22.53,;-10.63,-23.56,;-10.01,-24.97,;-8.47,-24.81,;-8.15,-23.3,)| Show InChI InChI=1S/C23H25F2N3O/c1-22(2,3)29-28-17-12-23(4,5)27-16-11-15(24)18(20(25)19(16)17)14-8-6-7-13-9-10-26-21(13)14/h6-11,26-27H,12H2,1-5H3/b28-17+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor in human NHDF cells assessed as inhibition of IL-1beta-stimulated AP1 dependent IL-6 repression b...				Bioorg Med Chem Lett 21: 1654-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.104 BindingDB Entry DOI: 10.7270/Q21V5F8D
					More data for this Ligand-Target Pair