Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50381744'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50381744 (CHEMBL2023620) Show SMILES C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=Cc5c(C[C@]34C)cnn5-c3ccc(F)cc3)[C@@H]1CC[C@]2(O)C(=O)CSc1ncccn1 |r,t:9| Show InChI InChI=1S/C32H35FN4O3S/c1-30-15-19-17-36-37(22-7-5-21(33)6-8-22)25(19)14-20(30)4-9-23-24-10-11-32(40,31(24,2)16-26(38)28(23)30)27(39)18-41-29-34-12-3-13-35-29/h3,5-8,12-14,17,23-24,26,28,38,40H,4,9-11,15-16,18H2,1-2H3/t23-,24-,26-,28+,30-,31-,32-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor in human H292 cells assessed as inhibition of TNF-induced IL8 production				Bioorg Med Chem Lett 22: 3291-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.015 BindingDB Entry DOI: 10.7270/Q2V69KMZ
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50381744 (CHEMBL2023620) Show SMILES C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=Cc5c(C[C@]34C)cnn5-c3ccc(F)cc3)[C@@H]1CC[C@]2(O)C(=O)CSc1ncccn1 |r,t:9| Show InChI InChI=1S/C32H35FN4O3S/c1-30-15-19-17-36-37(22-7-5-21(33)6-8-22)25(19)14-20(30)4-9-23-24-10-11-32(40,31(24,2)16-26(38)28(23)30)27(39)18-41-29-34-12-3-13-35-29/h3,5-8,12-14,17,23-24,26,28,38,40H,4,9-11,15-16,18H2,1-2H3/t23-,24-,26-,28+,30-,31-,32-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14.3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Transactivation activity at glucocorticoid receptor in rat H4II-E cells assessed as induction of tyrosineaminotransferase				Bioorg Med Chem Lett 22: 3291-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.015 BindingDB Entry DOI: 10.7270/Q2V69KMZ
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50381744 (CHEMBL2023620) Show SMILES C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=Cc5c(C[C@]34C)cnn5-c3ccc(F)cc3)[C@@H]1CC[C@]2(O)C(=O)CSc1ncccn1 |r,t:9| Show InChI InChI=1S/C32H35FN4O3S/c1-30-15-19-17-36-37(22-7-5-21(33)6-8-22)25(19)14-20(30)4-9-23-24-10-11-32(40,31(24,2)16-26(38)28(23)30)27(39)18-41-29-34-12-3-13-35-29/h3,5-8,12-14,17,23-24,26,28,38,40H,4,9-11,15-16,18H2,1-2H3/t23-,24-,26-,28+,30-,31-,32-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37.7	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Transactivation activity at glucocorticoid receptor in human HepG2 cells assessed as induction of tyrosineaminotransferase				Bioorg Med Chem Lett 22: 3291-5 (2012) Article DOI: 10.1016/j.bmcl.2012.03.015 BindingDB Entry DOI: 10.7270/Q2V69KMZ
					More data for this Ligand-Target Pair