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Found 1 hit Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50415801'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucocorticoid receptor


(Homo sapiens (Human))		BDBM50415801
PNG
(CHEMBL1093354)
Show SMILES CCn1ncc2c(Cl)c(cnc12)C(=O)NCc1cncs1
Show InChI InChI=1S/C13H12ClN5OS/c1-2-19-12-9(6-18-19)11(14)10(5-16-12)13(20)17-4-8-3-15-7-21-8/h3,5-7H,2,4H2,1H3,(H,17,20)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>6.31E+3n/an/an/an/an/an/a



Medicines Research Centre

Curated by ChEMBL


Assay Description
Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of cortisol-induced renilla luciferase transactiv...

Bioorg Med Chem Lett 20: 2340-3 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.133
BindingDB Entry DOI: 10.7270/Q2SF2XDJ
More data for this
Ligand-Target Pair