Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50416084'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50416084 (CHEMBL1083149) Show SMILES Fc1ccc(cc1)-n1ncc2cc(ccc12)-c1ccc(cc1C(F)(F)F)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C26H17F4N3O2S/c27-19-7-9-21(10-8-19)33-25-13-6-17(14-18(25)16-31-33)23-12-11-22(15-24(23)26(28,29)30)36(34,35)32-20-4-2-1-3-5-20/h1-16,32H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of fluorescent-labeled Dexamethasone from GR by fluorescent polarization assay				J Med Chem 53: 4531-44 (2010) Article DOI: 10.1021/jm100447c BindingDB Entry DOI: 10.7270/Q20003BB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50416084 (CHEMBL1083149) Show SMILES Fc1ccc(cc1)-n1ncc2cc(ccc12)-c1ccc(cc1C(F)(F)F)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C26H17F4N3O2S/c27-19-7-9-21(10-8-19)33-25-13-6-17(14-18(25)16-31-33)23-12-11-22(15-24(23)26(28,29)30)36(34,35)32-20-4-2-1-3-5-20/h1-16,32H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at GR in human A549 cells transfected with luciferase gene linked to MMTV promoter assessed as inhibition of dexamethasone-induce...				J Med Chem 53: 4531-44 (2010) Article DOI: 10.1021/jm100447c BindingDB Entry DOI: 10.7270/Q20003BB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50416084 (CHEMBL1083149) Show SMILES Fc1ccc(cc1)-n1ncc2cc(ccc12)-c1ccc(cc1C(F)(F)F)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C26H17F4N3O2S/c27-19-7-9-21(10-8-19)33-25-13-6-17(14-18(25)16-31-33)23-12-11-22(15-24(23)26(28,29)30)36(34,35)32-20-4-2-1-3-5-20/h1-16,32H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Activity at GR in human A549 cells by NF-kappaB transrepression assay				J Med Chem 53: 4531-44 (2010) Article DOI: 10.1021/jm100447c BindingDB Entry DOI: 10.7270/Q20003BB
					More data for this Ligand-Target Pair