BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glucokinase regulatory protein' and Ligand = 'BDBM50448563'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glucokinase regulatory protein (Homo sapiens (Human))	BDBM50448563 (CHEMBL3127347) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...				J Med Chem 57: 309-24 (2014) Article DOI: 10.1021/jm4016735 BindingDB Entry DOI: 10.7270/Q2KW5HJ4
Amgen, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Glucokinase regulatory protein (Rattus norvegicus)	BDBM50448563 (CHEMBL3127347) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.47E+3	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of GKRP-GK interaction in rat primary hepatocytes assessed as translocation of GK from nucleus to cytoplasm preincubated for 20 mins follo...				J Med Chem 57: 309-24 (2014) Article DOI: 10.1021/jm4016735 BindingDB Entry DOI: 10.7270/Q2KW5HJ4
Amgen, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair