BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glucose-dependent insulinotropic receptor' and Ligand = 'BDBM50128363'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50128363 (CHEMBL3629484) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 mins by fluorescence analysis				Bioorg Med Chem Lett 25: 5291-4 (2015) Article DOI: 10.1016/j.bmcl.2015.09.047 BindingDB Entry DOI: 10.7270/Q2QC05BG
Merck Research Laboratory Curated by ChEMBL					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Mus musculus)	BDBM50128363 (CHEMBL3629484) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	33	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 mins by fluorescence analysis				Bioorg Med Chem Lett 25: 5291-4 (2015) Article DOI: 10.1016/j.bmcl.2015.09.047 BindingDB Entry DOI: 10.7270/Q2QC05BG
Merck Research Laboratory Curated by ChEMBL					More data for this Ligand-Target Pair