BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glucose-dependent insulinotropic receptor' and Ligand = 'BDBM50342699'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glucose-dependent insulinotropic receptor (Mus musculus)	BDBM50342699 (5-chloro-2-(4-((1R,2S)-2-(2-(5-(methylsulfonyl)pyr...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Agonist activity at mouse GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...				Bioorg Med Chem Lett 21: 2665-9 (2011) Article DOI: 10.1016/j.bmcl.2010.12.086 BindingDB Entry DOI: 10.7270/Q2M61KJV
Merck& Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50342699 (5-chloro-2-(4-((1R,2S)-2-(2-(5-(methylsulfonyl)pyr...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...				Bioorg Med Chem Lett 21: 2665-9 (2011) Article DOI: 10.1016/j.bmcl.2010.12.086 BindingDB Entry DOI: 10.7270/Q2M61KJV
Merck& Co. Curated by ChEMBL					More data for this Ligand-Target Pair