Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Glutamate carboxypeptidase 2' and Ligand = 'BDBM456914'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM456914 (US10736974, Compound XY-43 | US10736974, Entry 17) Show SMILES OC(=O)CC[C@H](NC(=O)O[C@@H](CCCCNC(=O)c1ccc(I)cc1F)OC=O)C(O)=O |r| Show InChI InChI=1S/C19H22FIN2O9/c20-13-9-11(21)4-5-12(13)17(27)22-8-2-1-3-16(31-10-24)32-19(30)23-14(18(28)29)6-7-15(25)26/h4-5,9-10,14,16H,1-3,6-8H2,(H,22,27)(H,23,30)(H,25,26)(H,28,29)/t14-,16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
THE JOHNS HOPKINS UNIVERSITY US Patent					Assay Description The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...				US Patent US10736974 (2020) BindingDB Entry DOI: 10.7270/Q29C71GJ
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM456914 (US10736974, Compound XY-43 | US10736974, Entry 17) Show SMILES OC(=O)CC[C@H](NC(=O)O[C@@H](CCCCNC(=O)c1ccc(I)cc1F)OC=O)C(O)=O |r| Show InChI InChI=1S/C19H22FIN2O9/c20-13-9-11(21)4-5-12(13)17(27)22-8-2-1-3-16(31-10-24)32-19(30)23-14(18(28)29)6-7-15(25)26/h4-5,9-10,14,16H,1-3,6-8H2,(H,22,27)(H,23,30)(H,25,26)(H,28,29)/t14-,16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
THE JOHNS HOPKINS UNIVERSITY US Patent					Assay Description The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...				US Patent US10736974 (2020) BindingDB Entry DOI: 10.7270/Q29C71GJ
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase 2 (Homo sapiens (Human))	BDBM456914 (US10736974, Compound XY-43 | US10736974, Entry 17) Show SMILES OC(=O)CC[C@H](NC(=O)O[C@@H](CCCCNC(=O)c1ccc(I)cc1F)OC=O)C(O)=O |r| Show InChI InChI=1S/C19H22FIN2O9/c20-13-9-11(21)4-5-12(13)17(27)22-8-2-1-3-16(31-10-24)32-19(30)23-14(18(28)29)6-7-15(25)26/h4-5,9-10,14,16H,1-3,6-8H2,(H,22,27)(H,23,30)(H,25,26)(H,28,29)/t14-,16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
THE JOHNS HOPKINS UNIVERSITY US Patent					Assay Description The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...				US Patent US10736974 (2020) BindingDB Entry DOI: 10.7270/Q29C71GJ
					More data for this Ligand-Target Pair